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In spite of our best efforts Miss Taffy went to the Rainbow Bridge on April 4, 2000. I am leaving all the information up that I have about her illness because so many people have seen it and written to me and have found it useful. She is always in our hearts and we miss her terribly.

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The following is part of a letter I wrote to my friends about my Lhasa Apso, Miss Taffy. She is thought to be between 14 and 15 years old. I have had her 12 years and she has been a joy to live with for all these years but is starting to have serious problems. The letter explains the problems and below the letter there is a paper that my vet gave me to read that helps explain what is wrong with her. I am putting this web page up for those of you with older dogs who may be going through the same thing.

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I wrote to my friends:
"Many of you know that Miss Taffy has been acting pretty strange for a few months now. We have been taking her to the vet and having tests done and having consultations with other Vets so on. Taffy is not actually sick. Her heart, lungs, liver and kidneys are in excellent shape but she has totally lost her mind! She has no idea who Mom and I are most of the time. She hides from us behind the couch or under a bed or what ever is handy. We have to tag team her to even get a hold on her to give her medicine and she bites us any time we pick her up or even try to. She wants nothing to do with us at all. Giving her any kind of care or grooming is major event. She is right now taking Elavil which they often give dogs who have severe separation anxiety. She has only been on it for a couple of days so we don't know really if it will help but we doubt it will. She has also been taking a new drug for senility but it has not helped and actually seemed to make things worse.

The vet gave me a paper to read and I have scanned it and will attach it to this email just in case any of you want to read it. The general consensus is that she has what is called Cognitive Dysfunction Syndrome which is progressive and irreversible. What it is in a nutshell is that her body is healthy and her brain is going to pot. I didn't scan the whole paper my Vet gave me but it had pictures of dogs brains showing how parts of them get smaller and smaller so that the dog basically can't function in a normal way. Signs of it are "changes in the usual sleep wake cycle, such as increased daytime sleeping and less nighttime sleeping. Changes in interaction with the owner such as decreased greeting behavior. Signs of disorientation, such as becoming trapped in a corner or behind furniture or staring into space. Impairment in normal housetraining, with loss of signaling to go outdoors and house soiling. " That is exactly how Taffy started out but she is much worse now.

Most of you know that when we got Taffy no one really knew her age but best guess by 2 different vets was between 2 1/2 and 3 and we have had her 12 years. It is very distressing, depressing and many other things to know that she does not remember those years. She doesn't remember snuggling together on the bed sleeping in late on Sat. morning or going for car rides or any of the things she use to love. Most of all and most hurtful of all she does not remember that she loved us or how much we love her. Where she use to be delighted to even see us now she runs in fear from us. I didn't quite realize how deeply upset I am till I started to write this letter to you all. It is very difficult for me.

I have no idea what will happen. I pray that one of the medications will at least relieve her fear and give her some peace. She roams the house all night long just panting and huffing and puffing from being so stressed out. There is no comfort that we can give her, nothing helps her, we can't even hold her. She is so physically healthy that this could go on for a very long time."


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Taffy and Me

Miss Taffy and Me


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Cognitive Dysfunction Syndrome:


A New Look at "Old Dog" Syndrome


In dogs as in people, the medical implications of true aging are progressive and irreversible. Dogs reaching the final one-third of their lifespan undergo a variety of physical and metabolic changes that may cause them discomfort and/or change their behavior. For example, the acuity of the senses-sight, hearing, taste and smell-are reduced. Metabolism slows, immunocompetence decreases and tissues become dehydrated. Muscle and bone mass decline, and arthritis may affect the joints. There is an increased risk of cardiovascular disease, cancer and endocrine, renal and hepatic disorders.

The brain undergoes a series of changes that result in cognitive decline. It is generally believed-and studies have shown-that a dog's cognitive ability tends to decline with age. Cognitive function in dogs includes spatial orientation, housetraining, and recognizing and reacting to human family members. Cognitive Dysfunction Syndrome is the age-related deterioration of cognitive abilities characterized by behavioral changes in dogs that cannot be wholly attributed to general medical conditions such as neoplasia, infection or organ failure. CDS often is referred to by veterinarians as "old dog syndrome" or simply, "senility" and is manifested by one or more of the following five signs in the absence of any physical cause:

I. Disorientation/confusion
2. Decreased or altered responsiveness to family members
3. Disturbances of the sleep-wake cycle
4. Decreased activity level
5. Deterioration in housetraining

The progressive, degenerative course of canine CDS involves a gradual decline of cognitive ability sufficient to produce disfunctional ability in the home and/or as a family member. Dog owners may feel helpless, anxious and frustrated with the notion that the lifelong bonds they share with their canine companions are slipping away. While owners may be willing to tolerate some age-related behavioral problems associated with CDS, there eventually comes a time when those problematic behaviors become intolerable and euthanasia may be considered.

CDS Prevalence
Recently specialists have quantified the types and distribution of age-related behavior problems. An ongoing demographic study is being conducted at the University of California at Davis, investigating the incidence of signs associated with CDS in dogs between 11 and 16 years old. To date, a total of 139 dogs that had been patients at the Veterinary Medical Teaching Hospital have been evaluated: all were companion dogs that had received adequate veterinary care; the majority of males were neutered and the females spayed. It is important to note that none had a major debilitating general medical condition nor was undergoing drug therapy that might cause behavioral changes such as those being studied.

Following a screening interview, owners of the dogs were asked about the following:

I. Changes in the usual sleep-wake cycle, such as increased daytime sleeping and less nighttime sleeping
2. Changes in interactions with the owner such as decreased greeting behavior
3. Signs of disorientation, such as becoming trapped in corners or behind furniture or staring into space
4. Impairment in normal housetraining, with loss of signaling to go outdoors and house soiling

The UC-Davis CDS prevalence study revealed three major findings:
62% of 11- to 16-year-old dogs scored positively for one or more behavioral categories indicative of CDS. The prevalence of signs rose markedly with advancing age. No significant differences in incidence were seen between castrated males and spayed females within a given age group. From the data described above, we can assume that, as the population of older dogs increases, so will the number of CDS diagnoses made by veterinary practitioners. A 1998 market research study conducted by Pfizer Animal Health with dog owners supports the UC-Davis prevalence study findings. A total of 255 dog owners with dogs 8 years old and older were asked a detailed list of questions about their dog's behavior

The study found that:
48% of owners indicated their dog exhibited one or more clinical signs associated with CDS.
12% of surveyed pet owners described their dog as "senile."
73% of the remaining owners believed their dog "could develop senility."
81 % of dog owners who described their dog as senile indicated that their veterinarian was aware of the condition.

New Treatment
If your veterinarian has determined that your dog has CDS, a treatment for this disorder will probably be recommmended. A new drug called Selegiline or L-Deprenyl, (brand name Anipryl), although not a cure, has been shown to alleviate a some of the symptoms of CCD. If the dog responds, he will need to be treated daily for the rest of his life. As with all medications, there are side effects and dogs with certain conditions should not be given Anipryl. For instance, if your dog is on Mitaban for external parasites, Anipryl is contraindicated.

Summary
As a result of advancements in veterinary medical care, dogs are living longer. In fact, an estimated 13.6 million pet dogs in the United States are 8 years old or older which means a substantial number of senior canines are at risk for developing age-related behavioral and medical disorders.

CDS is a common, recognizable condition in senior dogs. Because older dogs are integral to the lives of millions of families, it is important that clients understand the difference between "normal aging" and age-associated medical and behavioral conditions such as CDS. Finally, because the syndrome is manifested through behavioral signs, the client plays a key role in identifying its signs and in bringing them to their veterinarian's attention.

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Just click on the cute puppy in the mailbox to E-mail me!

Rott Pup In Mailbox
(Graphic Courtesy Of ©Peggy Rose)



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See the update on Miss Taffy-High Blood Pressure In Dogs


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